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Fresh off it's 2022 Canadian Podcast Award win for "Outstanding Science Series" the production team at Behind the Breakthrough is busy at work on a brand new season of the podcast dedicated to showcasing groundbreaking medical research and the people behind it at UHN.
Season 5 is set to launch October 10, 2023 and features an all-star cast of award winning UHN researchers including Princess Margaret Senior Scientists Dr. Gelareh Zadeh, who achieved a world first when her lab successfully mapped the biology of meningiomas, the most common form of brain tumour, and, Dr. Laurie Ailles, who also scored a research first when she discovered the origin cell of head and neck squamous carcinoma.
Listeners will also hear about some of the outside-the-box research UHN champions in an effort to expand the mission of Canadian hospitals and lead in a collaborative way to generate solutions that address the root causes of health problems. This includes in-depth conversations with Dr. Andrew Boozary, a pioneer of the concept of social medicine and a driving force in this country to improve the health outcomes of disadvantaged populations, and, Dr. Howard Abrams, a leader in the establishment of naturally occurring retirement communities (NORCS) for seniors.
Join us on this acclaimed podcast and come on a journey of discovery this season with UHN's Behind the Breakthrough!
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Episode 10 – Dr. Shaf Keshavjee takes us behind the breakthrough of his lung transplant discoveries
Air Date: December 14, 2022 |
Length: 59:06 |
Download the transcript
UHN surgeon scientist Dr Shaf Keshavjee sits down with
Behind the Breakthrough host Christian Coté and takes us on a behind-the-scenes journey of his groundbreaking medical discoveries – two of which have had a profound impact on lung transplant around the world. For his Master's thesis in the late 1980's he developed a lung preservation solution – LDP – which is now the standard for lung preservation worldwide. Twenty years later he followed that up with the invention of a lung perfusion machine that preserves and treats damaged donor lungs outside the body – or
ex vivo. The Toronto Ex Vivo Lung Perfusion System has doubled the number of lungs available for transplant and is now in use around the world. Today the system is being tested to treat other damaged organs including the liver, kidney, and heart. In this wide-ranging and revealing conversation, Dr. Keshavjee speaks to the importance of mentorship, the qualities necessary to be a successful scientist, and, the importance of scientists learning about patenting and commercializing their work. Dr. Keshavjee also talks about a big personal motivation in his career trajectory - the inspiration he derives from his parents sacrifice. When he was just 12 years old they sold their dream house and quit their jobs in Nairobi, Kenya to move to Canada and start over in the hopes of giving their son and daughter better educational and life opportunities. Don't miss this compelling episode featuring an up-close conversation with Dr. Shaf Keshavjee.
Listen to the full episode and subscribe wherever you get your podcasts.
Episode 9 – Dr. Michael Reber and pioneering the use of virtual reality devices to restore visionAir Date: December 7, 2022 | Length: 41:54
Learn more about Dr. Reber & listen to the episode
Episode 8 – Dr. Rama Khokha on her breakthrough to map the biology of pancreatic cancerAir Date: November 30, 2022 | Length: 34:50
Learn more about Dr. Khokha & listen to the episode
Episode 7 – Dr. Lorraine Kalia and a promising new treatment for Parkinson's DiseaseAir Date: November 23, 2022 | Length: 41:54
Learn more about Dr. Kalia & listen to the episode
Episode 6 – Dr. Eleanor Fish on therapeutic benefit of interferons against virusesAir Date: November 16, 2022 | Length: 31:49
Learn more about Dr. Fish & listen to the episode
Episode 5 – Dr. Jonathan Irish and augmented reality in cancer surgeryAir Date: November 9, 2022 | Length: 46:54
Learn more about Dr. Irish & listen to the episode
Episode 4 – Dr. Carmela Tartaglia and pioneering a diagnosis for CTEAir Date: November 2, 2022 | Length: 43:57
Learn more about Dr. Tartaglia & listen to the episode
Episode 3 – Dr. Andrea Iaboni and a new toolkit for LTC to help care of residents during an outbreakAir Date: October 26, 2022 | Length: 33:56
Learn more about Dr. Iaboni & listen to the episode
Episode 2 – Dr. Gordon Keller on his groundbreaking research to advance stem cell-based therapiesAir Date: October 19, 2022 | Length: 43:23
Learn more about Dr. Keller & listen to the episode
Episode 1 – Dr. Andrea Furlan on groundbreaking new treatments for chronic painAir Date: October 12, 2022 | Length: 1:01:41
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Episode 10 – Dr. Angela Cheung pioneers research on the symptoms and treatment for long-hauler COVID patientsAir Date: December 14, 2021 | Length: 40:56
Learn more about Dr. Cheung & listen to the episode
Episode 9 – Dr. Andres Lozano on investigating DBS to treat Alzheimer's diseaseAir Date: December 7, 2021 | Length: 38:35
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Episode 8 – Dr. Babak Taati on pioneering the use of computer vision to help seniors live safer, healthier lives Air Date: November 30, 2021 | Length: 34:36
Learn more about Dr. Taati & listen to the episode
Episode 7 – The 'Biomarker Hunter' – searching for the genetic and immune system abnormalities that lead to systemic autoimmune rheumatic diseases Air Date: November 23, 2021 | Length: 37:58
Learn more about Dr. Wither & listen to the episode
Episode 6 – Dr. Gang Zheng on harnessing the promise of nanotechnology for the detection and treatment of cancer Air Date: November 16, 2021 | Length: 52:10
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Episode 5 – Dr. Jordan Feld on shifting from discovering a pill that cures Hepatitis C to investigating a treatment for mild COVID Air Date: November 9, 2021 | Length: 53:10
Learn more about Dr. Feld & listen to the episode
Episode 4 – Dr. Catherine O'Brien on the world-first discovery that colorectal cancer cells hibernate like bears to evade chemotherapy Air Date: November 2, 2021 | Length: 44:44
Learn more about Dr. O'Brien & listen to the episode
Episode 3 – Dr. Deepali Kumar on world-first discovery that third COVID-19 vaccine dose significantly boosts protection for transplant patients Air Date: October 26, 2021 | Length: 28:05
Learn more about Dr. Kumar & listen to the episode
Episode 2 – Dr. Beate Sander on the economics of infectious diseases and guiding public health policy during the COVID-19 pandemic Air Date: October 19, 2021 | Length: 47:21
Learn more about Dr. Sander & listen to the episode
Episode 1 – UHN's world leading COVID-19 research; the triumph of basic science in creating the vaccine; and when will the pandemic end? Air Date: October 12, 2021 | Length: 54:52
Learn more about Dr. Wouters & listen to the episode
Episode 10 – Dr. John Dick on his famous discovery of cancer stem cells, and the puzzle of research Air Date: November 26, 2020 | Length: 1:15:06
Learn more about Dr. Dick & listen to the episode
Episode 9 — Dr. Mansoor Husain on a breakthrough drug for diabetes and heart disease Air Date: | Length:
Learn more about Dr. Husain & listen to the episode
Episode 8 – Dr. Alex Mihailidis on helping us live at home longer Air Date: November 19, 2020 | Length: 45:02
Learn more about Dr. Mihailidis & listen to the episode
Episode 7 – Dr. Ralph DaCosta on a better way to visualize cancer and his serendipitous invention Air Date: November 17, 2020 | Length: 41:48
Learn more about Dr. DaCosta & listen to the episode
Episode 6 – Dr. Sonya MacParland on developing the world's first map of the liver Air Date: November 12, 2020 | Length: 42:52
Learn more about Dr. MacParland & listen to the episode
Episode 5 – Dr. Heather Baltzer on pioneering hand trauma treatment Air Date: November 10, 2020 | Length: 31:26
Learn more about Dr. Baltzer & listen to the episode
Episode 4 – Dr. Pamela Ohashi on treating cancer with immunotherapy Air Date: November 5, 2020 | Length: 28:05
Learn more about Dr. Ohashi & listen to the episode
Episode 3 – Dr. Taufik Valiante invents computer chip designed to monitor and stop epileptic seizures Air Date: November 3, 2020 | Length: 52:27
Learn more about Dr. Valiante & listen to the episode
Episode 2 – Turning stem cells into pacemaker cells, with Dr. Stephanie Protze Air Date: October 29, 2019 | Length: 30:27
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Episode 1 – Dr. Brad Wouters on leadership during the pandemic, COVID-19 research, and anti-vaxxers Air Date: October 27, 2020 | Length: 46:35
Episode 11 – Beating back Alzheimer's, one poem at a time, with Dr. Donald Weaver Air Date: December 17, 2019 | Length: 37:14
Learn more about Dr. Weaver & listen to the episode
Episode 10 — Using computers to understand cancer with Dr. Michael Hoffman Air Date: December 10, 2019 | Length: 31:00
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Episode 9 — Pioneering research by UHN's Dr. Kristin Musselman is designed to get spinal cord injured patients mobile Air Date: December 3, 2019 | Length: 30:22
Learn more about Dr. Musselman & listen to the episode
Episode 8 — Reversing blindness and the serendipity of science, with Dr. Valerie Wallace Air Date: November 26, 2019 | Length: 35:04
Learn more about Dr. Wallace & listen to the episode
Episode 7 – Repairing broken hearts with stem cells, with Dr. Michael Laflamme Air Date: November 19, 2019 | Length: 28:22
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Episode 6 – Overcoming 'imposter syndrome' and helping the elderly live well, with Dr. Jennifer Campos Air Date: November 12, 2019 | Length: 40:02
Learn more about Dr. Campos & listen to the episode
Episode 5 – Meet the cancer codebreaker, Dr. Mathieu Lupien Air Date: November 5, 2019 | Length: 47:38
Learn more about Dr. Lupien & listen to the episode
Episode 4 – Robotics, rehabilitation therapy and learning from failure, with Dr. Milos Popovic Air Date: October 29, 2019 | Length: 32:03
Learn more about Dr. Popovic & listen to the episode
Episode 3 – Challenging the meaning of palliative care, with Dr. Camilla Zimmermann Air Date: October 22, 2019 | Length: 43:20
Learn more about Dr. Zimmermann & listen to the episode
Episode 2 – Chronic pain and scientific baseball, with Dr. Karen Davis Air Date: October 15, 2019 | Length: 34:56
Learn more about Dr. Davis & listen to the episode
Episode 1 – Dr. Heather Ross on heart failure, artificial intelligence and a near-death experience Air Date: October 8, 2019 | Length: 42:07
Learn more about Dr. Ross & listen to the episode