Our Vision
To implement Artificial Intelligence (AI) into transplant care.
With the confluence of AI expertise in Toronto and the largest transplant program in North America, we are working toward leading the world in AI tool development and implementing these tools in the clinical setting.
Our Goals
Our Transplant AI initiative is based on a solid foundation of clinical knowledge, computer science and data analytics and will facilitate advancements in the four major fields of interest:
Donor/recipient matching
- Donor selection is a challenging and multifactorial decision influenced by both donor and recipient factors as well as match considerations.
- Machine learning models can analyze a wide range of donor and recipient characteristics and detect complex nonlinear relationships between input variables to identify the most compatible matches.
- We intend to use machine learning to optimize donor-recipient matching and increase post-transplant survival.
Prioritization of organ allocation
- Allocation process is complex and involves many variables.
- AI can help optimize the allocation process by uncovering non-linear and subtle correlations among these variables that cannot be identified using conventional analysis models.
- AI has the potential to improve efficiency and fairness of organ allocation process.
- AI can be used to develop predictive models that can identify patients who are at highest risk of mortality or dropout.
Long-term post-transplant complications
- Long-term survival compromised by cardiovascular, cancer, infection and graft failure-associated mortality.
- AI trained on large datasets can identify patterns and associations to predict outcomes.
- Opportunity for individualized prevention or intervention plan for transplant recipients based on the top-ranked modifiable features.
Equity for organ allocation
- Inequities in organ allocation due to various factors such as sex, gender, race, ethnicity, socioeconomic status, and access to healthcare.
- AI could help address inequities in organ allocation process by enabling more accurate and efficient organ matching.
Our Core Values
Collaboration
Partner with patients, health teams, researchers and industry to improve the success of solid organ transplantation and the quality of life for transplant recipients.
Communication & Transparency
Raise awareness and share knowledge regarding transplant research and its advancements.
Research and Innovation
By leveraging AI technologies, we aim to optimize organ allocation, improve patient outcomes and increase the efficiency of the transplant process.
Leadership
Guide the development and implementation of machine learning models and other AI techniques to improve outcomes for transplant patients.
Equity & Advocacy
Develop strategies to improve quality and quantity of life of our patients regardless of sex, race, gender, or other such factors and move towards a more equitable care.
Our Team
Our team brings together a wide range of unique expertise in clinical care, research, and artificial intelligence.
