Correlative Studies Program
The CCRU Correlative Studies Program provides services and expertise to facilitate all aspects of biospecimen management for clinical trials, such as bio-specimen collection, processing, handling, storage, shipping, tracking and documentation.
The Correlative Studies Program provides services to an average of 80 new clinical trials each year, as well as continuing services for up to 200 ongoing clinical studies. Each year, we collect and process the following for pharmacokinetic, pharmacodynamic, pharmacogenomic, and biomarker evaluation studies:
- 75 fresh tumour biopsies
- 100 skin biopsies
- 650 archival tissue specimens
- 20 bone marrow specimens
- 8,000 blood samples
The program draws on highly skilled correlative research technicians, who provide consistency in the procurement process to ensure high-integrity, high-quality biospecimens for correlative studies, and a correlative research coordinator, who facilitates pre-screening procedures for patients who require mutational analysis of their archived tumour tissue prior to registration.
All staff are trained on study-specific protocol procedures, institutional laboratory guidelines, Good Clinical Practices, Good Laboratory Practices and departmental Standard Operating Procedures.
We maintain a Level II laboratory available to all other clinical research personnel processing blood specimens.
For additional information about our services, please contact us at CCRUcorrelativestudies@uhn.ca.