The Dental Oncology and Maxillofacial Prosthetics Clinic aims to push the frontiers of clinical and translational research in our field. We aim to provide cutting-edge treatment and management in rehabilitation as well as medical, surgical and radiation oncology.
Our team’s current studies include:
- Assessment of different staging systems of osteoradionecrosis.
- Assessment of osteoradionecrosis incidence in patients treated for head and neck cancer.
Clinical practice guidelines for dental management prior to radiation for head and neck cancer.
Oladega, A. et. al. The Process of Developing Consensus Guidelines by Dental Oncologists for Pre-Radiotherapy Dental Care in Head and Neck Cancer Patients Using the Modified Delphi Technique. J Evid Base Dent Pract. 2021, 21(4). https://doi.org/10.1016/j.jebdp.2021.101620
Watson, E.E. et al. Canadian Dental Oncology Network Consensus Group. Clinical practice guidelines for dental management prior to radiation for head and neck cancer. Oral Oncology. 2021, 123. https://doi.org/10.1016/j.oraloncology.2021.105604
- Cell-free DNA early detection of oral squamous cell carcinomas utilizing saliva and blood liquid biopsies.
- Dental examination and treatments of patients planned for cardiac surgeries.
- Investigating the role of oral innate immune system and oral microbiome in recovery in bone marrow transplant patients.
- Investigating the role of oral inflammation and microbiome in cardiovascular patients undergoing cardiac surgery for LVAD placement and/or heart transplant.
- Microbial collection and analyses from the surface of tumours biopsied from head and neck cancer patients.
Prevalence of oral lesions in and dental needs of patients with newly diagnosed acute leukemia.
Watson, E.E. et. al. Screening for Dental Infections Achieves 6-Fold Reduction in Dental Emergencies During Induction Chemotherapy for Acute Myeloid Leukemia. JCO Oncology Practice. 2020, 16(11).
- Success and survival of dental implants in patients with maxillofacial prostheses.
- The association between the socioeconomic status and the development of osteoradionecrosis of the jaw in patients with have received radiation therapy to the head and neck.
- The development of medication-induced osteoradionecrosis of the jaw (MRONJ) after dental extractions.
The DMFS160: A new index for measuring post-radiation crisis.
Watson, E. et. al. The DMFS160: A new index for measuring post-radiation caries. Oral Oncol. 2020, 108. https://doi.org/10.1016/j.oraloncology.2020.104823
The effect of ionizing radiation on the oral innate immune response, oral microbiome and the Quality of Life in Patients Undergoing Head and Neck Intensity-Modulated Radiotherapy for the Treatment of Head and Neck Tumours.
Mojdami, Z.D. et al. The Effect of Intensity-Modulated Radiotherapy to the Head and Neck Region on the Oral Innate Immune Response and Oral Microbiome: A Prospective Cohort Study of Head and Neck Tumour Patients. Int. J. Mol. Sci. 2022, 23, 9594. https://doi.org/10.3390/ijms23179594
- The potential correlation between periodontal status and graft versus host disease in allogenic bone marrow transplant recipients.
The Timing of Extractions Prior to Radiation Therapy Does Not Influence the Development of Osteoradionecrosis.
Oral Abstract Presentation -Dr. Junhyung John Lee. The Timing of Extractions Prior to Radiation Therapy Does Not Influence the Development of Osteoradionecrosis. American Association of Oral and Maxillofacial Surgeons Annual Meeting 2022, New Orleans, Louisiana. September 16, 2022.
- Third molar incidence and localization in patients receiving oncologic, cardiac and transplant therapies and determination of associated delay in medical treatment.