​​ We ask researchers to acknowledge the Leukemia Tissue Bank at Princess Margaret Cancer Centre / University Health Network as the source for primary AML samples and clinical data in publications.

Below are representative published papers that have used Leukemia Tissue Bank samples and data.



PRMT5 regulates ATF4 transcript splicing and oxidative stress response. Szewczyk MM, Luciani GM, Vu V, Murison A, Dilworth D, Barghout SH, Lupien M, Arrowsmith CH, Minden MD, Barsyte-Lovejoy D.Redox Biol. 2022 May;51:102282.​

Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21)AML. Krivdova G, Voisin V, Schoof EM, Marhon SA, Murison A, McLeod JL, Gabra MM, Zeng AGX, Aigner S, Yee BA, Shishkin AA, Van Nostrand EL, Hermans KG, Trotman-Grant AC, Mbong N, Kennedy JA, Gan OI, Wagenblast E, De Carvalho DD, Salmena L, Minden MD, Bader GD, Yeo GW, Dick JE, Lechman ER.Cell Rep. 2022 Mar 8;38(10):110481. ​

Avocado-derived avocadyne is a potent inhibitor of fatty acid oxidation. Tcheng M, Minden MD, Spagnuolo PA.J Food Biochem. 2022 Mar;46(3):e13895​

Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia. Tuval A, Brilon Y, Azogy H, Moskovitz Y, Leshkowitz D, Salame TM, Minden MD, Tal P, Rotter V, Oren M, Kaushansky N, Shlush LI.Haematologica. 2022 Feb 24. doi: 10.3324/haematol.2021.280329.

Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux. Dotan I, Yang J, Ikeda J, Roth Z, Pollock-Tahiri E, Desai H, Sivasubramaniyam T, Rehal S, Rapps J, Li YZ, Le H, Farber G, Alchami E, Xiao C, Karim S, Gronda M, Saikali MF, Tirosh A, Wagner KU, Genest J, Schimmer AD, Gupta V, Minden MD, Cummins CL, Lewis GF, Robbins C, Jongstra-Bilen J, Cybulsky M, Woo M.Commun Biol. 2022 Feb 15;5(1):132.

SmMIP-tools: a computational toolset for processing and analysis of single-molecule molecular inversion probes derived data. Medeiros JJF, Capo-Chichi JM, Shlush LI, Dick JE, Arruda A, Minden MD, Abelson S.Bioinformatics. 2022 Feb 12;38(8):2088-95.

IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells. Nachmias B, Khan DH, Voisin V, Mer AS, Thomas GE, Segev N, St-Germain J, Hurren R, Gronda M, Botham A, Wang X, Maclean N, Seneviratne AK, Duong N, Xu C, Arruda A, Orouji E, Algouneh A, Hakem R, Shlush L, Minden MD, Raught B, Bader GD, Schimmer AD.Leukemia. 2022 Feb 12.

A clinical laboratory-developed LSC17 stemness score assay for rapid risk assessment of patients with acute myeloid leukemia. Ng SWK, Murphy T, King I, Zhang T, Mah M, Lu Z, Stickle N, Ibrahimova N, Arruda A, Mitchell A, Mai M, He R, Madala BS, Viswanatha DS, Dick JE, Chan S, Virtanen C, Minden MD, Mercer T, Stockley T, Wang JCY.Blood Adv. 2022 Feb 8;6(3):1064-1073.

An improved molecular inversion probe based targeted sequencing approach for low variant allele frequency. Biezuner T, Brilon Y, Arye AB, Oron B, Kadam A, Danin A, Furer N, Minden MD, Hwan Kim DD, Shapira S, Arber N, Dick J, Thavendiranathan P, Moskovitz Y, Kaushansky N, Chapal-Ilani N, Shlush LI.NAR Genom Bioinform. 2022 Feb 8;4(1):lqab125.

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target. Vanner RJ, Dobson SM, Gan OI, McLeod J, Schoof EM, Grandal I, Wintersinger JA, Garcia-Prat L, Hosseini M, Xie SZ, Jin L, Mbong N, Voisin V, Chan-Seng-Yue M, Kennedy JA, Waanders E, Morris Q, Porse B, Chan SM, Guidos CJ, Danska JS, Minden MD, Mullighan CG, Dick JE.Blood Cancer Discov. 2022 Jan;3(1):16-31.​


Complete Publications List

We encourage you to explore a more complete list of publications that have used Leukemia Tissue Bank samples and data.

View more publications


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Last reviewed: 4/27/2022
Last modified: 4/28/2022 12:26 PM