At UHN, we strive to deliver Compassionate Care & Caring. Learn more about the services and supports that are available to you throughout your journey.
Our UHN programs and services are among the most advanced in the world. We have grouped our physicians,
staff, services and resources into 10 medical programs to meet the needs of our patients and help us make
the most of our resources.
At the heart of everything we do at UHN are our Healthcare Professionals. Refer a patient to one of our 12 medical programs. Learn more about the resources and opportunities available for professional growth.
University Health Network has grown to be one of the largest research and teaching hospital networks in Canada - pioneers in improving the lives of patients. Our long history of health professions education at Toronto General, Toronto Western, Princess Margaret and Toronto Rehab hospitals has consistently advanced the science of education.
University Health Network is a health care and medical research organization in
Toronto, Ontario, Canada. The scope of research and complexity of cases at UHN has made us a national and international
source for discovery, education and patient care.
Being touched by illness affects us in different ways. Many people want to give back to the community
and help others. At UHN, we welcome your contribution and offer different ways you can help so you can find one that suits you.
The Newsroom is the source for media looking for information about UHN or trying to connect with one
of our experts for an interview. It's also the place to find UHN media policies and catch up on our news stories, videos, media releases,
podcasts and more.
Toronto (March 19, 2007) - Survivors of Hodgkin's lymphoma (HL), a cancer that affects the young, are at substantially increased risk of developing second cancers later in life, shows a major international study of 18,862 HL survivors.
The study evaluated cumulative risks up to 30 years after the initial diagnosis of HL and found that the incidence of all cancer types evaluated was significantly higher than normal, except for bladder and prostate cancers. Female survivors aged 40 or older who had been diagnosed with HL at age 30 had a 6-fold increase in breast cancer risk. Other forms of cancer were increased up to 20-fold. At about age 70, risks decline, but do not return to normal levels.
Lead author Dr. David Hodgson, a PMH radiation oncologist, noted that this problem was particularly dramatic for women diagnosed with HL at a young age, "We estimated that almost 25% of women diagnosed with HL at age 20 would develop a second cancer by age 50." In the general population, this rate is expected to be less than 5%, he said.
The study examined the risks of colorectal and breast cancers in detail because of the possibility that screening may help detect these cancers at an early stage. In Canada, colorectal and breast cancer screening is recommended for most adults in the general population starting at age 50. "For many HL survivors, the risk of colorectal cancer in their mid-30's is comparable to that of an average 50-year-old. The risk of breast cancer in young women was also significantly elevated five to 10 years after their lymphoma diagnosis, often years before the age when routine screening would be recommended."
Says Dr. Hodgson: "The results suggest that some HL survivors should be considered for breast and colorectal cancer screening sooner than the age of routine screening."
The paper will be published online today in the Journal of Clinical Oncology, and in the print edition April 20, 2007.
Princess Margaret Hospital and its research arm, Ontario Cancer Institute, have achieved an international reputation as global leaders in the fight against cancer. Princess Margaret Hospital is a member of the University Health Network, which also includes Toronto General Hospital and Toronto Western Hospital. All three are research hospitals affiliated with the University of Toronto.
Phone: 416 340 4636