Our UHN programs and services are among the most advanced in the world. We have grouped our physicians, staff, services and resources into 10 medical programs to meet the needs of our patients and help us make the most of our resources.
University Health Network is a health care and medical research organization in Toronto, Ontario, Canada. The scope of research and complexity of cases at UHN has made us a national and international source for discovery, education and patient care.
Our 10 medical programs are spread across eight hospital sites – Princess Margaret, Toronto General, Toronto Rehab’s five sites, Toronto Western – as well as our education programs through the Michener Institute of Education at UHN. Learn more about the services, programs and amenities offered at each location.
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When a person has a heart attack, working cardiac muscle dies and is replaced by scar tissue. Treatments are few and those that are available are mostly aimed at slowing the progression of the patient's underlying heart disease, rather than restoring function to the damaged part of the heart.
But what if doctors could inject heart muscle cells derived from stem cells into the ailing organ to repair it? That is the question Dr. Michael Laflamme has been working on for nearly his entire research career.
In 2015, Laflamme came to Toronto from the University of Washington to further his work in cardiac regenerative medicine. Soon after his arrival, he was named to head an interdisciplinary team of investigators funded by the University of Toronto's Medicine by Design initiative to fast-track cardiac cell therapy.
"I think things are going well," says Laflamme, the Robert R. McEwen Chair in Cardiac Regenerative Medicine at the
McEwen Centre for Regenerative Medicine and a senior scientist at University Health Network's
Toronto General Hospital Research Institute.
Laflamme, who is also an associate professor at U of T's
Department of Laboratory Medicine & Pathobiology, put together a team of about two dozen scientists that includes three co-principal investigators, as well as post-doctoral fellows and graduate students.
Using a variety of non-human studies, team members are working to overcome important but surmountable hurdles that lie in the way of using stem cell-derived cardiac muscle cells, or cardiomyocytes, to repair damaged muscle after a heart attack.
Read more about the Medicine by Design team projects