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Our Leadership

Robert Inman, Co-Director, Schroeder Arthritis Institute

Summary

Our research program focuses on resolving the pathogenesis and defining the optimal management of ankylosing spondylitis (AS).

The basic science approaches include molecular biology, genomics and proteomics as applied to animal models of AS and to immunophenotyping of cells from AS patients.

The clinical studies include defining prognostic factors in AS, response profiles to biologic agents, and decision analysis in diagnostic algorithms.

Team Members

Michael Tang, Postdoctoral Fellow
Zoya Qaiyum, Graduate Student
Melissa Lim, Lab Technician
Ali Akram, Postdoctoral Fellow
Anthony So, Graduate Student
Ejaz Pathan, Clinical Research Fellow
Gillian Fitzgerald, Clinical Research Fellow
Daeria Lawson, Graduate Student
Sophie Wojcik, Clinical Research Fellow
Aki Nakamura, Clinical Research Fellow

Keywords

Immunology; genetics; spondylitis; inflammation; cytokines

Profiles

Mohit Kapoor, Co-Director, Schroeder Arthritis Institute

Summary

Dr. Kapoor is the Co-Director of the Schroeder Arthritis Institute. He is the Tony and Shari Fell Platinum Chair in Arthritis Research - Canada Research Chair (Tier 1), a Professor at the University of Toronto and a Senior Scientist at the Krembil Research Institute.

Dr. Kapoor’s translational research program is directed towards:

Understanding the complex cellular and molecular mechanisms associated with joint destruction during osteoarthritis.
Identifying reliable biomarkers for early identification of patients with osteoarthritis to enable early intervention.
Identifying novel therapeutic targets to stop/delay osteoarthritis and restore joint function.
Understanding key endogenous mechanisms associated with fibrosis during osteoarthritis and connective tissue diseases.

Team Members

Dr. Jason Rockel, Scientific Associate
Dr. Starlee Lively, Scientific Associate
Dr. Anusha Ratneswaran, Postdoctoral Fellow
Dr. Ghazaleh Tavallaee, PhD
Brian Wu, PhD Candidate
Evgeny Rossomacha, Histo-Technologist
Dr. Osvaldo Espin-Garcia, Biostatistician
Pratibha Potla, Bioinformatician
Kim Perry, Research Manager
Sarah Gabrial, Administrative Assistant

Keywords

Cartilage degeneration; fibrosis; biomarkers; genetically modified mice; OA tissue biobanking

Research Lab

Profiles

Research Profile

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