ALERT CONTENT PLACEHOLDER

Sent on behalf of Dr. Mohit Kapoor and Dr. Robert Inman, Co-Directors of the Schroeder Arthritis Institute, UHN

We are delighted to share the December 2023 edition of our newsletter with you. Dr. Mohit Kapoor & Dr. Robert Inman, Co-Directors of the Schroeder Arthritis Institute
Arthritis Program Newsletter
Happy Holidays! On Behalf of the SAI, we wish you Happy Holidays and a New Year full of happieness and success!


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The Schroeder Arthritis Institute Newsletter

If you have any news, upcoming publications, awards and grants, promotions, or new appointments, please email them to Lynn Saber, Digital Content & Communication Specialist at the Schroeder Arthritis Institute: Lynn.Saber@uhn.ca.


SPECIAL FEATURES


The special features included in each newsletter highlight some of the outstanding individuals who have contributed immensely towards the success of each division of the Schroeder Arthritis Institute. Our September newsletter feature highlighted Jean Nisbet and Jin Xuetong. If you have missed this feature. If you have missed this feature, please follow this link.

In this edition, we are highlighting two exceptional individuals who have made an outstanding impact towards the growth and success of the Schroeder Arthritis Institute.

Luis Montoya

Luis Montoya  

Luis Montoya is the Research Manager within the Division of Orthopedics at the Schroeder Arthritis Institute. Originally from Colombia, Luis was a dentist back home. After arriving to Canada, he decided to take a new path within the healthcare field and completed a postgraduate program in clinical research. He joined the University Health Network (UHN) as a volunteer in 2012 with the Ophthalmology Department and joined the Division of Orthopedics in 2013 as a research assistant. In 2014, he was promoted to research coordinator, where he had the opportunity to lead the LEAP OA Study within the division. He later pursued a Project Management certificate at the University of Toronto and in 2018 came into his current position as research manager. Some of Luis's key responsibilities include overseeing the research activities in close collaboration with all the investigators and research staff, fostering collaborations between all the teams within the division and working on developing grants and research proposals. Luis also plays a key role in staff development and in ensuring all resources are in place to conduct project plans and achieve their desired outcomes. In addition, Luis works in conjunction with the principal investigators within the Division of Orthopedics to review and manage both short- and long-term plans that align with all four of our Institute's divisions and the University Health Network's goals and strategies. He also manages finances for the division, and interacts with stakeholders, external partners and the UHN internal legal departments.

A big change that Luis has been a part of is the integration of research and clinical work. He is working on Quality Improvement (QI) Projects and translating all of the information from research to be able to implement the information on the clinical side. One QI project he is now a part of is called Patient Experience, a survey-based approach that is used to better understand the patient's journey starting from the moment they have been referred to the clinic.

"My motivation is rooted in understanding that I play an integral role within our extraordinary and multidisciplinary team, that are collectively dedicated to advancing patient care, with the goal of making a positive transformation in patient care." When asked what his Mantra of Success is, Luis emphasized, "There are no stop signs on the road to success." He has an unwavering commitment to life-long learning and is always trying to learn new things. Since 2008, Luis has been doing systematic reviews on his free time. He started working with a team from McMaster University and got over 20 papers published in high impact journals. He enjoys learning new things and participating in systematic reviews on various topics is one way he learns more.

Luis is a very friendly individual. "I'm someone that says good morning to everyone and I try to teach this kindness to my kids." He's very caring in nature and this reflects in his position as a manager. He is very understanding and always wants to ensure that his team is doing well. Luis is also a very hard worker. He continues to learn each day and to give his best in everything that he does, whether in his professional position or at home with his family.

Growing up, Luis loved to play soccer everyday. His first-choice career during school was to become a professional soccer player and he even had the opportunity to join a professional team in Colombia, although he joined dentistry instead. To this day, Luis continues to play soccer and is the soccer coach for both of his young children in soccer leagues. He enjoys coaching them and spending this quality time together playing a sport they all love and teaching them his knowledge and skills.

Luis greatly expressed how blessed he feels to be a part of the team at Schroeder Arthritis Institute. "It's all about the vision that the Institute has, caring for patients, and trying to find a cure to improve healthcare worldwide. I feel lucky to be part of our astonishing team. This team is a family, and when you are in a family you care about each other and that's what we do."

On behalf of the Schroeder Arthritis Institute, we are grateful for Luis's exceptional contributions to the growth and success of the Institute.


Nicole Villamonte  

Nicole Villamonte is the Clinical Research Manager for the Lupus Program within the Division of Rheumatology at the Schroeder Arthritis Institute. She is also responsible for managing the Rheumatology Clinical Trial Unit. Nicole joined the Lupus Program 13 years ago as a research associate and then moved into her current role in 2015. As a clinical research manager, she works closely with Dr. Zahi Touma, the Director of the Lupus Program, and she is responsible for overseeing multiple aspects of the program. Nicole plays a key role in securing grant funding for the team, administration of grant funds, and ensures that projects run effectively. She also seeks out collaborative opportunities for projects that can foster the Lupus Program at the Institute's national and international visibility. Nicole also manages the Lupus Program team, which involves assigning projects and tasks to team members as well as supporting the team with anything they may need. Within the Rheumatology Clinical Trial unit, she works closely with her team to ensure that the trials successfully recruit patients, provides financial management and helps manage trials from the start-up phase to the closeout phase, ensuring all is running smoothly.

Nicole's biggest motivation is knowing that she plays a key role in ensuring patients will receive the best care. "I am passionate about impacting our patient's wellbeing and their quality of life. I want to see all of those aspects for our patients and their families increase and really make a positive difference for them." When asked what her Mantra of Success is, Nicole said, "Empower, innovate and lead." Nicole positively takes on any changes that her team faces and tries to turn them into opportunities for growth. She hopes to inspire her team the same way her team inspires her.

Nicole is an optimistic person. She tries to always find the bright side of each situation whether in her work or in her personal life. She's been described as being diplomatic within her workplace setting as she always wants to ensure that there is clear communication between each team member. Nicole also finds herself to be very relatable to many people. "I think because I have such long-standing experience in research, from being an analyst, coordinator, and associate, to manager, I have different ways of understanding how each of those roles work. When someone comes to me with an issue, I have the understanding to help them."

A fun fact about Nicole is that she loves spending time with her little dog named Peanut. She is also a very creative person. In her free time, she enjoys painting and all things art. Nicole also has a passion for interior design and has a small interior design business as well, you can check it out on Instagram.


NEW APPOINTMENTS & PROMOTIONS


Business Manager - Krembil Research Institute

Kim Perry  

The Schroeder Arthritis Institute would like to thank Kim Perry, former Biobank Manager for the Division of Orthopedics' Schroeder Arthritis Institute Biobank, and Lab Manager for Dr. Mohit Kapoor's Lab, at the Institute, for all of her exceptional contributions to the success of the Institute for almost 10 years.

Kim began her career in 2014 for the Division of Orthopedic's Biobank where she had many responsibilities such as collecting, processing, data management as well as storage of high quality specimens for the Biobank. She worked very closely with the orthopedic research team and was in constant communication with the clinical teams to ensure that all tasks were being accomplished efficiently such as consenting patients for blood, tracking and maintaining surgical patients and communicating with end users to make sure they receive the samples they need. As Lab Manager, Kim maintained all equipment, ethical protocols and basic procurement such as ordering and finance. Kim also facilitated all ongoing projects in the lab. In addition, she was also the Co-Chair of the Schroeder Arthritis Institute Biobank Committee.

We would also like to congratulate Kim on her new role as Business Manager at the Krembil Research Institute and wish her all the success in her new role.


Hand and Wrist Surgeon - Hand Program

Dr. Jonathan Persitz  

Dr. Jonathan Persitz recently joined the Hand Program at the Schroeder Arthritis Institute as a Staff Hand and Wrist Surgeon. Dr. Persitz is a Summa Cum Laude medical school graduate. He completed his Orthopedic Surgery residency in Israel, received additional hand surgery training in Switzerland and the United Kingdom, and earned a national award for his outstanding performance in the Orthopedic Surgery Board Examination. He then pursued dual fellowships in hand and upper extremity surgery in Israel, and in hand and peripheral nerve surgery within the Hand Program at the Institute. Dr. Persitz is currently pursuing a Master of Science degree at the University of Toronto, focusing on enhancing the quality of care and functional outcomes in relation to distal radius fractures.


Administrative Coordinator for SAI Outpatients

Stetson Ford  

Stetson Ford was recently promoted to Administrative Coordinator for SAI Outpatients at the Schroeder Arthritis Institute. Stetson joined the Orthopedic Inpatient Unit back in 2010 as a casual clerk and found different ways to incorporate patient care within his role. He later moved to an Administrative Assistant role in 2018 and has recently joined his new role as the administrative coordinator, where he continues to find the best ways to support the team and make a positive change for patient care.


Medical Administrative Assistant - Hand Program

Cherry Abugan  

Cherry Abugan recently joined the Hand Program at the Schroeder Arthritis Institute as a Medical Administrative Assistant to Dr. Kevin Zuo. Cherry is a former volunteer and intern at the Toronto General Hospital Thrombosis and Hemostasis Program. She graduated as a Medical Office Administrator at Media College of Healthcare in 2017. She previously worked as a Medical Office Assistant/Medical Secretary, in Access Alliance Multicultural Health & Community Services, Clanton Park Family Medicine of North York Family Health Team, & Dr. Robert Barry Miller ENT/Otolaryngology Office.


Medical Administrative Assistant - Hand Program

Jhanna Bermudez  

Jhanna Bermudez recently joined the Hand Program at the Schroeder Arthritis Institute as a Medical Administrative Assistant to Dr. Ryan Paul. Jhanna initially joined the University Health Network in 2017 as a Full Time Medical Administrative Assistant in Neurosurgery and then transferred to the Hand Program in 2019, managing the office of Dr. Paul. She recently returned from Maternity leave. She holds a Bachelor of Science and has experience in management.


Project Manager - Division of Orthopedics

Dr. Priyanka Kugamoorth  

Dr. Priyanka Kugamoorthy recently joined the Division of Orthopedics at the Schroeder Arthritis Institute as a short-term Project Manager in Dr. Sowmya Viswanathan's lab. Her role will primarily involve working on a clinical trial application amendment to Health Canada as a part of the ABLE-OA study. Dr. Kugamoorthy holds a Doctor of Medicine, has undergone clinical training out of Chicago & Toronto, and has simultaneously contributed to the University Health Network's research facilities for over seven years.


AWARDS AND RECOGNITIONS


UHN Local Impact Award - University Health Network

Silvi Groe  

Silvi Groe, Clinical Director at the Schroeder Arthritis Institute, was recently awarded the UHN Local Impact Award at the University Health Network Week of Gratitude, for her dedication to the arthritis team. She provides opportunities and experiences that help build a culture of joy and empower our team such as Joy in the Workplace.


Leadership Award - Division of Orthopedics, Schroeder Arthritis Institute

Dr. Wayne Marshall  
Dr. Nizar Mahomed  

Dr. Wayne Marshall and Dr. Nizar Mahomed, Orthopedic Surgeons within the Division of Orthopedics at the Schroeder Arthritis Institute, were recently awarded with the Leadership Award at the Academic Advisory Board Meeting 2023, for the Division of Orthopaedics at the Schroeder Arthritis Institute. This award recognized their visionary leadership in establishing the Arthritis Program at the University Health Network.


Global Impact Award - University Health Network

Dr. Murray Urowtiz  

Dr. Murray Urowtiz, former Director of the Lupus Program within the Division of Rheumatology at the Schroeder Arthritis Institute, was recently awarded the Global Impact Award at the University Health Network Week of Gratitude, for his many contributions to advancing medical care and discovery.


2023 Master in Rheumatology - American College of Rheumatology

Dr. Jorge Sanchez-Guerrero  

Dr. Jorge Sanchez-Guerrero, Clinician Investigator within the Division of Rheumatology at the Schroeder Arthritis Institute, was recently awarded the 2023 Master in Rheumatology Award by the American College of Rheumatology (ACR) at the ACR Convergence Meeting that took place in November 2023.


Chair, Dr. Murray B. Urowitz Chair in Lupus Research

Dr. Zahi Touma  

Dr. Zahi Touma, Director of the Lupus Program within the Division of Rheumatology at the Schroeder Arthritis Institute, was recently appointed to the inaugural Dr. Murray B. Urowitz Chair in Lupus Research at the University Health Network. This will allow him to develop and lead innovative research that supports the prevention, diagnosis and treatment of patients with Lupus.


Chair in Musculoskeletal and Postmenopausal Health

Dr. Angela Cheung  

Dr. Angela Cheung, Director of the Osteoporosis Program at the Schroeder Arthritis Institute, was recently awarded Tier 1 Canada Research Chair in Musculoskeletal and Postmenopausal Health. The Chair will support research to better understand musculoskeletal and postmenopausal health, with a focus on bone and muscle strength and function, in healthy aging, osteoporosis, atypical femur fractures, rare bone diseases and in common general medical conditions such as diabetes and post-COVID condition.


Best Female Scientists in Canada 2023

Dr. Dafna Gladman  

Dr. Dafna Gladman, Senior Scientist within the Division of Rheumatology at the Schroeder Arthritis Institute, was recently recognized in the Top 3 Best Female Scientists in Canada in 2023, and in the Top 100 worldwide. Learn more here.


Best Clinical Research Presentation - National Institutes of Health (NIH) Conference

Laura Passalent  

Laura Passalent, Physiotherapist Practitioner and Clinician Investigator at the Schroeder Arthritis Institute, was recently awarded the Best Clinical Research Presentation award at the National Institutes of Health Conference that took place on September 28 to September 29, 2023, in Washington, for her project titled "Design Thinking Applied to Unmet Needs in Axial Spondyloarthritis: A Novel Model of Care to Address Diagnostic Delay."


GRANTS


Grant - ERA-NET Neuron
Grant - Ontario Research Fund

Dr. Igor Jurisica  

Dr. Igor Jurisica, Senior Scientist within the Division of Orthopedics at the Schroeder Arthritis Institute, recently received a grant from ERA-NET Neuron for a project he is a co-principal investigator for titled Disease-predisposing or resilience-promoting? Decoding the systems biology and behavioural predictors and determinants of the tipping point of stress.

Dr. Jurisica also received a grant from the Ontario Research Fund for a project is he co-principal investigator for titled The Fibrosis Repair Team.


THINC Implementation Science Team Grant - Canadian Institutes of Health Research, Institute of Musculoskeletal Health and Arthritis (CIHR-IMHA)

Laura Passalent  
Leslie Soever  

Laura Passalent, Physiotherapist Practitioner and Clinician Investigator at the Schroeder Arthritis Institute, and Leslie Soever, Physiotherapist Practitioner at the Schroeder Arthritis Institute, recently received THINC Implementation Science Team Grant from the Canadian Institutes of Health Research, Institute of Musculoskeletal Health and Arthritis (CIHR-IMHA) for a project they were co-investigators for titled The Ontario Rheumatology Learning Health System for Transforming Integrated Care for Patients with Rheumatic and Musculoskeletal Disorders.


TRAINEE/FELLOW SPOTLIGHT


Dr. Mauro Maniglio

Dr. Mauro Maniglio  

Dr. Mauro Maniglio is a Clinical Fellow within the Hand Program at the Schroeder Arthritis Institute, supervised by Dr. Heather Baltzer, Director of the Hand Program. Dr. Maniglio came from Switzerland about three months ago with the goal of learning new techniques from the outstanding surgeons within the Hand Program, to gain greater experience and to learn from theirs. He has a variety of roles within the clinic, from seeing patients, assisting surgeons in the operating room, to performing surgery alongside the team. He has had the opportunity to work closely with Dr. Heather Baltzer and Dr. Andrea Chan in many different areas.

In addition to clinical work, Dr. Maniglio is doing research alongside Dr. Baltzer and Danny Antflek, the Clinical Research Coordinator for the Hand Program. This research started while Dr. Maniglio was still in Switzerland and continues to flourish as they now work side by side. The research is mainly surrounding basis of thumb osteoarthritis, searching for systemic biomarkers in the blood of the patients with the potential to foresee the clinical outcome of the affected patients after an adapted treatment.

Looking towards the future, Dr. Maniglio hopes to continue working in a large university hospital in Switzerland, in a leading position and in an academic field, doing clinical work in hand surgery as well as continuing to pursue research goals.

A fun fact about Dr. Maniglio is that he is a big adventurer. "After completing medical school, I cycled along the Mediterranean Sea with a bicycle in 15 months, visiting 21 countries in Europe, North Africa, the Middle East and the Balkan." He also crossed the Atlantic Ocean with a sailing boat in three months. His latest adventure is coming to Toronto, Canada, and living abroad with his family, his wife and two young children, and not only advancing his experiences within his work but also exploring what Toronto has to offer. "A big part of experience is family. The adventure to be abroad and to be in a new environment is really amazing."

Dr. Maniglio is extremely thankful to have this opportunity with the Institute and to have the chance to collaborate and work closely with our inspiring team within the Hand Program and hopes to stay in close contact in the future.

You can connect with Dr. Maniglio and follow his research updates on LinkedIn and on Research Gate.

On behalf of the Schroeder Arthritis Institute, we are grateful that Dr. Maniglio is part of our team and wish him all the success in his future.


Zack Willson  

Zack Willson is a third year Undergraduate Student supervised by Dr. Andy Wong within the Osteoporosis Program at the Schroeder Arthritis Institute. He is currently completing his third year in the Engineering Science program at the University of Toronto, majoring in math, and statistics and finance, while doing a minor in artificial intelligence engineering. He is also part of a team at the University of Toronto working on a project of building a satellite.

His research at the Institute within the Osteoporosis Program with Dr. Andy Wong started in May 2022. The research surrounds analyzing bone metabolism in post-menopausal women with osteoporosis and/or osteoarthritis. They are analyzing their standard uptake values to determine any correlation between bone metabolism and osteoporosis and/or osteoarthritis. In addition to this research, he had the opportunity to branch out and work on other projects within the team. He gained machine learning experience by working on 2D-3D convolutional neural networks with other team members.

Looking towards the future, Zack hopes to work in a field that primarily involves math and coding, similar to the work that he has been doing in his research with Dr. Wong at the Institute.

A fun fact about Zack is that he is the Co-Captain of the tennis team at the University of Toronto, and they have recently won gold for Ontario just a month ago. He has been playing tennis all of his life in different leagues and it is truly something he loves. "It is definitely neat to now work on osteoarthritis projects given that this can affect many players in tennis."

Zack is very thankful to have the opportunity to do research with the Osteoporosis Program and be part of the exceptional team at the Institute. This research project is something he really enjoys and plans on continuing to pursue.

You can connect with Zack and follow his research updates on LinkedIn.

On behalf of the Schroeder Arthritis Institute, we are grateful that Zack is part of our team and wish him all the success in his future.


STUDENT AWARDS


Best Basic Science Presentation - National Institutes of Health (NIH) Conference

Addison Pacheco  

Addison Pacheco, Graduate Student at the Schroeder Arthritis Institute, supervised by Dr. Robert Inman, was recently awarded the Best Basic Science Presentation Award at the National Institutes of Health Conference which took place on September 28 to September 29, 2023, in Washington, for his project titled "Reduced Frequency of RORγt+ Regulatory T Cells is Associated with Secukinumab Response in Axial Spondyloarthritis."


Gini M. Finzi Summer Fellowship Award - Lupus Foundation of America

Atoosa Ziyaeyan  
Griffin Copp  
Dr. Shahrzad Nouri  
Ian Herrera  

The team ArthroFlora by Atoosa Ziyaeyan, Ph.D. Student, Griffin Copp, Master's Student, Dr. Shahrzad Nouri, Postdoctoral Fellow, and Ian Herrera, Research Technician, supervised by Dr. Sowmya Viswanathan within the Division of Orthopaedics at the Schroeder Arthritis Institute, have been selected to participate in 2023-2024 Building a Biotech Venture Program offered by Medicine by design to develop customized probiotics capable of modulating immune effectors in osteoarthritis.


ARTHRITIS IN THE NEWS


The State of Arthritis in Canada Report Card

The State of Arthritis in Canada Report Card  

The Arthritis Community Research and Epidemiology Unit (ACREU) group at the Schroeder Arthritis Institute, co-directed by Dr. Anthony Perruccio and Dr. Elizabeth Badley, made a significant contribution to the first ever "The State of Arthritis in Canada Report Card", released by the Arthritis Society Canada.

Dr. Anthony Perruccio, Senior Scientist, Dr. Elizabeth Badley, Senior Emeritus, and Jessica Wilfong, Research Associate, at the Schroeder Arthritis Institute, made significant contributions to the Report Card.

Learn more here.

Read the document here.


Article - Advancing Arthritis Research

Drs. James Young and Michael Zywiel  

Dr. James Young, Postdoctoral Researcher in Integrated Arthritis Care, supervised by Dr. Michael Zywiel and Dr. Anthony Perruccio, at the Schroeder Arthritis Institute, and Dr. Michael Zywiel, Clinician Investigator within the Division of Orthopedics at the Schroeder Arthritis Institute, are advancing osteoarthritis research through detailed analysis of patient data. They are characterizing participants in a program that is aimed at providing guidance for non-surgical Osteoarthritis care - GLA:D® Canada.

Read the article here.

Read the publication here.


Krembil Annual Report 2023

Krembil Annual Report 2023 - Breakthroughs for Tomorrow  

Inspiration, dedication and discovery. Read the Krembil Research Institute's 2023 Annual Report #BreakthroughsForTomorrow, showcasing the incredible research being done at the Schroeder Arthritis Institute, University Health Network, the multidisciplinary teams that make it possible, and the science and innovation that is paving the way for a healthier future.

Explore our Institute's latest research achievements that are shaping the landscape of science and medicine: Read the Annual Report Here.


EDUCATION CORNER


Schroeder Arthritis Institute Education - Helga and Anthony DeGasperis Fund Grants

 
 
 
 
 

The Schroeder Arthritis Institute Education Committee is excited to announce the following successful recipients of Helga and Anthony DeGasperis Fund Grants for Education - Related Projects and Endeavours:

Laura Passalent, Physiotherapist Practitioner and Clinician Investigator at the Institute, and Dr. Nigil Haroon, Head of the Division of Rheumatology at the Institute, recently received the grant for their project titled "We Got Your Back, version 2.0: Pan-Canadian implementation as evaluation of an e-learning patient education program in Axial Spondyloarthritis."

Dr. Katerina Oikonomopoulou, Research Education Lead and Scientific Associate at the Institute, recently received the grant for the "2023-2024 Internship Program for Schroeder Arthritis Institute Trainees and Research Staff."

Dr. Barbara Jemec, Hand Surgeon within the Hand Program at the Schroeder Arthritis Institute, recently received the grant for "Education-related equipment for the Hand Program."

Congratulations to all the grant recipients! It has been very exciting to see the innovative and important projects that are being submitted for consideration.

Dr. Lori Albert and Laura Passalent,
Education Leads, Schroeder Arthritis Institute


RECENT EVENTS & LECTURES


Academic Advisory Board Meeting 2023 - Division of Orthopedics, Schroeder Arthritis Institute

The Osteoarthritis Research Program within the Division of Orthopedics at the Schroeder Arthritis Institute held the 2023 Academic Advisory Board (AAB) Meeting on November 1-2, 2023, in Toronto. This marked the first in-person gathering since the onset of the pandemic.

Our team met with the distinguished Academic Advisory Board, comprised of renowned experts in the field, including Dr. Robin Poole (Chair), Professor Emeritus at McGill University, Dr. Elena Losina, Robert W. Lovett Professor of Orthopedic Surgery at Harvard University, Dr. Stefan Lohmander, Senior Professor Emeritus at Lund University, Dr. Frank Barry, Professor at the National University of Ireland, Galway, Dr. Regis O'Keefe, Fred C. Reynolds Professor at Washington University in St. Louis, and Dr. Joseph Buckwalter, Professor at the University of Iowa.

During the meeting, the esteemed board actively listened to multiple research studies, engaged in discussions and expressed enthusiasm for the remarkable progress observed within the Division of Orthopedics. The integration of research and clinical care was particularly highlighted as a driving force behind impressive advancements in the field.

This meeting was co-chaired by Dr. Raja Rampersaud, Director of the Osteoarthritis Research Program, Dr. Christian Veillette, Head of the Division of Orthopaedics at the Schroeder Arthritis Institute, and Dr. Mohit Kapoor, Co-Director of the Schroeder Arthritis Institute.

Academic Advisory Board Meeting Group


The Annual Ralph T. Manktelow Lectureship in Hand Surgery

The Annual Ralph T. Manktelow Lectureship in Hand Surgery was held on November 3, 2023, at Toronto Rehab Institute. The Lecture was a great success thanks to the excellent speakers including Visiting Professor Dr. Mark Baratz, Clinical Professor in the Department of Orthopedics at the University of Pittsburgh and Director of the Hand and Upper Extremity Fellowship who presented, "It's all about harmony". Dr. Ralph Manktelow attended and he and Dr. Heather Baltzer, Director of the Hand Program and Head of Plastic and Reconstructive Surgery at the Schroeder Arthritis Institute, presented Dr. Baratz with the inaugural Manktelow Award. Dr. Baltzer wishes to thank all attendees and looks forward to seeing all next year on November 15, 2024, at the BMO Education and Conference Centre at Toronto Western Hospital.

Dr. Mark Baratz, Dr. Ralph Manktelow and Dr. Heather Baltzer


National Institutes of Health (NIH) Conference

The Spondylitis Program team within the Division of Rheumatology at the Schroeder Arthritis Institute attended the National Institutes of Health Conference in Bethesda, Maryland, on September 28-29, 2023. The theme of the conference was "Unmet Research Needs in Spondyloarthritis." The Spondylitis Program from the Schroeder Arthritis Institute had the highest number of trainees in attendance, and Addison Pacheco, Graduate Student supervised by Dr. Robert Inman at the Schroeder Arthritis Institute, received the Best Research Presentation award at the meeting.

The Spondylitis Program team


Brachial Plexus and Nerve Transfer Course

Dr. Barbara Jemec, Hand Surgeon within the Hand Program at the Schroeder Arthritis Institute, arranged the Hand Program's first of its kind brachial plexus and nerve transfer course in the Skills Lab at Mount Sinai Hospital. This was also thanks to the help of the wonderful staff at the Skills Lab, including Jason Faria, Dr. Kevin Zuo and Dr. Heather Baltzer. The course inaugurated AV equipment, made possible through a generous education grant from the Schroeder Arthritis Institute.

Brachial Plexus and Nerve Transfer Course


SPARCC Annual Scientific Meeting 2023

The Spondyloarthritis Research Consortium of Canada (SPARCC), at the Schroeder Arthritis Institute, a trans-disciplinary national research program focusing on "Genetic and Pathogenesis Studies and Outcome Measures for Patients with Spondyloarthritis (SpA)", successfully conducted its annual scientific meeting on October 27, 2023 at the Courtyard Marriott Downtown Toronto.

SPARCC principal investigators spearheaded by Drs. Robert Inman and Dafna Gladman at the UHN core site along with its co-investigators - Drs. Vinod Chandran and Nigil Haroon, as well as collaborating investigators and its research associates/coordinators from across Canada, delegates from its patient advocacy group – the Canadian Spondyloarthritis Association (CSA), and distinguished guests from SPARCC's valued industry sponsors participated. At this meeting, the many research breakthroughs of SPARCC for the past year(s) were unveiled.

The overall objective of the SPARCC research program is to improve the health of SpA patients in Canada by better defining, diagnosing, and predicting the course of ankylosing spondylitis (AS) and psoriatic arthritis (PsA). SpA has a significant prevalence and high burden of illness in the Canadian population. SPARCC addresses the biological basis of SpA and its impact on individuals and society through a multidisciplinary approach, which draws expertise from across the spectrum of health research. The results of the SPARCC program will have important implications with respect to benefits for Canada.

SPARCC Annual Scientific Meeting 2023


SPARCC - CSA Patient Symposium 2023

The Spondyloarthritis Research Consortium of Canada (SPARCC), at the Schroeder Arthritis Institute, in collaboration with the Canadian Spondyloarthritis Association (CSA), hosted a hybrid Spondyloarthritis Patient Symposium focusing on Axial Spondyloarthritis on November 6, 2023, at the BMO Education and Conference Center.

Dr. Robert Inman, Co-Director of the Schroeder Arthritis Institute, Dr. Nigil Haroon, Head of the Division of Rheumatology at the Schroeder Arthritis Institute, and Laura Passalent, Physiotherapist Practitioner and Clinician Investigator at the Schroeder Arthritis Institute, were the expert leads and keynote speakers representing SPARCC.

CSA & SPARCC 2023 Spondyloarthrtis Patient Forum


UHN Summit on Quality and Safety

The University Health Network (UHN) hosted its 2nd annual UHN Summit on Quality and Safety on November 15, 2023. Silvi Groe, Clinical Director of the Schroeder Arthritis Institute (SAI), Samra Mian-Valiante, Director of Strategy & Transformation at the SAI, and Camille Orridge, SAI Patient Partner and Health Equity Co-Lead, had the opportunity to share the quality framework developed by the Schroeder Arthritis Institute, showcasing key learnings that we gained through the process that will support other programs across UHN in their journey towards improving quality care and the experiences of our patients and our team.

Learn more about our quality framework here.

UHN Summit on Quality and Safety


Psoriatic Arthritis Program Annual Team Meeting

The Schroeder Arthritis Institute's Psoriatic Arthritis Program within the Division of Rheumatology held their annual Psoriatic Arthritis Program Team Meeting on October 12, 2023, at the BMO Education & Conference Center. The annual event includes all members of the research team including collaborators from Cambridge University, United Kingdom, and the University of Waterloo Biostatistics Units, trainees, staff and members of the patient advisory committee.

Psoriatic Arthritis Program Annual Team Meeting


Research Trainee & Staff Career Development Seminar

Research Trainee & Staff Career Development Seminar  

The Schroeder Arthritis Institute hosted a virtual Research Trainee & Staff Career Development Seminar on October 17, 2023. Our invited speaker, Dr. Sonya MacParland, Scientist at the Toronto General Research Institute, University Health Network, CRC Tier 2 in Liver Immunobiology, and Associate Professor at the University of Toronto, presented on "Multi-omic approaches to study cellular ecosystems in liver disease."




Metabolomics Workshop

Metabolomics Workshop  

The Schroeder Arthritis Institute in partnership with the University Health Network Office of Research Trainees hosted a virtual workshop on "Metabolomics: An Emerging Tool in Biomedical Research." This two hour event took place on October 4, 2023, and highlighted information about the Schroeder Arthritis Institute's Metabolomics Core Facility and ways on how one can incorporate metabolomics within research.




UPCOMING EVENTS & LECTURES


3rd International Workshop on the Epigenetics of Osteoarthritis

Join us for the 3rd International Workshop on the Epigenetics of Osteoarthritis, September 4-5, 2024, in Toronto, Canada! This two-day in-person workshop will feature world leading experts in the fields related to epigenetic mechanisms associated with osteoarthritis. The workshop will be an excellent platform for research researchers, trainees and fellows to meet with the international leaders in this field.

Registration and Abstract Submission opens on February 1, 2024.

Please visit our website for registration and all workshop updates and information -> https://www.epigeneticsoa.com

For any questions, please email epigeneticsoa@gmail.com

#EpigeneticsOA2024

3rd International Workshop on the Epigenetics of Osteoarthritis


International Women & Girls in Science Virtual Event

The Krembil Research Institute's annual virtual event for students celebrating the International Day of Women and Girls in Science, will happen on February 9th, 2024, from 10-11am ET. This 1-hour live stream is geared to middle school, high school & undergraduate students, and is meant to inspire young minds to consider a career in science & medicine. Each speaker will give a short, engaging TED Talk-style presentation, followed by a panel discussion answering questions sent in by students.

Featured speakers include: Drs. Tina Felfeli (Donald K. Johnson Eye Institute), Nikita Looby (Schroeder Arthritis Institute) and Nardin Samuel (Krembil Brain Institute) and our host/moderator this year is Dr. Chika Stacy Oriuwa. Watch for more information on Twitter & LinkedIn. Registration details to follow!

#WomenInScience


ARTHRITIS WEB SEMINAR SERIES - RECENT LECTURES


Arthritis Web Seminar Series - Lecture 59

 

The Schroeder Arthritis Institute, in partnership with the Collaborative Specialization in Musculoskeletal Sciences, University of Toronto, hosted the 59th Arthritis Web Seminar Series Lecture on October 10, 2023. Our guest speaker, Dr. Cristina Ruiz-Romero, Academic Researcher at Galician Health Service in Coruña University in Spain, gave a seminar on "Emerging proteomic and metabolomic biomarkers in rheumatic diseases."

Click here to watch the recorded seminar.


Arthritis Web Seminar Series - Lecture 60

 

The Schroeder Arthritis Institute, in partnership with the Collaborative Specialization in Musculoskeletal Sciences, University of Toronto, hosted the 60th Arthritis Web Seminar Series Lecture on November 28, 2023. Our guest speaker, Dr. Cornelia Weyand, Professor of Medicine and Research Chair of the Division of Rheumatology in the Department of Internal Medicine at Stanford University, gave a seminar on "Large Vessel Vasculitis - A Disease of Lost Inhibition."

Click here to watch the recorded seminar.


ARTHRITIS WEB SEMINAR SERIES - UPCOMING LECTURES


Arthritis Web Seminar Series - Lecture 61

 

The Schroeder Arthritis Institute will be hosting the 61st Arthritis Web Seminar Series Lecture on January 23, 2024. Our guest speaker, Dr. James Chang, Chair of the Division of Plastic & Reconstructive Surgery and Johnson & Johnson Distinguished Professor at Stanford University, will give a seminar on "Update on Hand Surgery for System Sclerosis."


NOTABLE PUBLICATIONS


Efficacy of Guselkumab on Axial-Related Symptoms Through up to 2 Years in Adults with Active Psoriatic Arthritis in the Phase 3, Randomized, Placebo-Controlled DISCOVER-2 Study.

Mease PJ, Gladman DD, Poddubnyy D, Chakravarty SD, Shawi M, Kollmeier AP, Xu XL, Xu S, Deodhar A, Baraliakos X. Rheumatol Ther. December 2023. Click here for publication.


Association of Synovial Fluid and Urinary C2C-HUSA levels with Surgical Outcomes Post-Total Knee Arthroplasty.

Sandhu A, Espin-Garcia O, Rockel J, Lively S, Perry K, Mahomed N, Rampersaud YR, Perruccio A, Poole R, Gandhi R, Kapoor M. Osteoarthritis and Cartilage. October 2023. Click here for publication.


Editorial: Metabolic response: nexus or nemesis for the understanding of sports nutrition and doping

Muniz-Santos R, Watt P, Jurisica I, Cameron LC. Front Nutr. October 2023. Click here for publication.


EULAR recommendations for the management of systemic lupus erythematosus: 2023 update

Fanouriakis A, Kostopoulou M, Andersen J, Aringer M, Arnaud L, Bae SC, Boletis J, Bruce IN, Cervera R, Doria A, Dörner T, Furie RA, Gladman DD, Houssiau FA, Inês LS, Jayne D, Kouloumas M, Kovács L, Mok CC, Morand EF, Moroni G, Mosca M, Mucke J, Mukhtyar CB, Nagy G, Navarra S, Parodis I, Pego-Reigosa JM, Petri M, Pons-Estel BA, Schneider M, Smolen JS, Svenungsson E, Tanaka Y, Tektonidou MG, Teng YO, Tincani A, Vital EM, van Vollenhoven RF, Wincup C, Bertsias G, Boumpas DT. Ann Rheum Dis. October 2023. Click here for publication.


From Microcosm to Macrocosm: The -Omics, Multiomics, and Sportomics Approaches in Exercise and Sports

Muniz-Santos R, Magno-França A, Jurisica I, Cameron LC. OMICS. November 2023. Click here for publication.


Functional and patient-reported outcomes following single digit replantation: A systemic literature review

Persitz J, Khan S, Kim G, Alhujayri AK, Lorquet E, Baltzer H. Hand Surg Rehabil. October 2023. Click here for publication.


Generalized pustular psoriasis: A consensus statement from the National Psoriasis Foundation

Armstrong AW, Elston CA, Elewski BE, Ferris LK, Gottlieb AB, Lebwohl MG; Medical Board of the National Psoriasis Foundation. J Am Acad Dermatol. October 2023. Click here for publication.


GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets

Dand N, Stuart PE, Bowes J, Ellinghaus D, Nititham J, Saklatvala JR, Teder-Laving M, Thomas LF, Traks T, Uebe S, Assmann G, Baudry D, Behrens F, Billi AC, Brown MA, Burkhardt H, Capon F, Chung R, Curtis CJ, Duckworth M, Ellinghaus E, FitzGerald O, Gerdes S, Griffiths CEM, Gulliver S, Helliwell P, Ho P, Hoffmann P, Holmen OL, Huang ZM, Hveem K, Jadon D, Köhm M, Kraus C, Lamacchia C, Lee SH, Ma F, Mahil SK, McHugh N, McManus R, Modalsli EH, Nissen MJ, Nöthen M, Oji V, Oksenberg JR, Patrick MT, Perez-White BE, Ramming A, Rech J, Rosen C, Sarkar MK, Schett G, Schmidt B, Tejasvi T, Traupe H, Voorhees JJ, Wacker EM, Warren RB, Wasikowski R, Weidinger S, Wen X, Zhang Z; BSTOP study group; Estonian Biobank research team; Barton A, Chandran V, Esko T, Foerster J, Franke A, Gladman DD, Gudjonsson JE, Gulliver W, Hüffmeier U, Kingo K, Kõks S, Liao W, Løset M, Mägi R, Nair RP, Rahman P, Reis A, Smith CH, Di Meglio P, Barker JN, Tsoi LC, Simpson MA, Elder JT. medRxiv. October 2023. Click here for publication.


Hospital spending and length of stay attributable to preoperative adverse events for inpatient hip, knee, and spine surgery: a retrospective cohort study.

Rampersaud Y.R, Sundararajan K, Docter S, Perruccio A.V, Gandhi R, Adams D, Briggs N, Davey J.R, Fehlings M, Lewis S.J, Magtoto R, Massicotte E, Sarro A, Syed K, Mahomed N.N, Veillette C. BMC Health Services Research. October 2023. Click here for publication.


Identifying Serum Metabolomics Markers Associated with Skin Disease Activity in Patients with Psoriatic Arthritis

Choksi H, Li S, Looby N, Kotlyar M, Jurisica I, Kulasingam V, Chandran V. Int J Mol Sci. October 2023. Click here for publication.


Incidence and predictors of demyelinating disease in Spondyloarthritis: data from a longitudinal cohort study.

Remalante-Rayco P, Espiritu AI, Daghistani Y, Chim T, Atenafu E, Keshavarzi S, Jha M, Gladman DD, Oh J, Haroon N, Inman RD. Rheumatology (Oxford). October 2023. Click here for publication.


Increased risk of severe generalized pustular psoriasis due to tuberculosis screening delay for spesolimab initiation.

Hackley M, Thampy D, Waseh S, Feldman SR, Blauvelt A, Weinberg JM, Schwartzman S, Liao W, Prussick R, Cohen JM, Hsu S; National Psoriasis Foundation Medical Board. J Am Acad Dermatol. October 2023. Click here for publication.


Long-term humoral and cellular immunity after primary SARS-CoV-2 infection: a 20-month longitudinal study.

Hvidt AK, Guo H, Andersen R, Lende SSF, Vibholm LK, Søgaard OS, Schleimann MH, Russell V, Cheung AM, Paramithiotis E, Olesen R, Tolstrup M. BMC Immunology Journal. November 2023. Click here for publication.


More Evidence on the Validity of the Measurement Properties of PROMIS Computerized Adaptive Tests in Systemic Lupus Erythematosus.

Touma Z, Parodis I, Strand V. J Rheumatol. November 2023. Click here for publication.


PathDIP 5: Improving coverage and making enrichment analysis more biologically meaningful

Pastrello C, Kotlyar M, Abovsky M, Lu R, Jurisica I.Nucleic Acids Res. November 2023. Click here for publication.


Patient clusters indented by machine learning from a pooled analysis of the clinical development programme of secukinumab in psoriatic arthritis, ankylosing spondylitis and psoriatic arthritis with axial manifestations

Baraliakos X, Pournara E, Coates LC, Mease PJ, Jahandideh SS, Gladman D. Clin Exp Rheumatol. November 2023. Click here for publication.


Pharmacodynamic effects of filgotinib treatment driving clinical improvement in patients with active psoriatic arthritis enrolled in the EQUATOR trial.

Chandran V, Malkov VA, Ito KL, Liu Y, Vestergaard L, Yoon OK, Liu J, Trivedi M, Hertz A, Gladman D. RMD Open. November 2023. Click here for publication.


Proceedings of the International Society for Cell & Gene Therapy Annual Meeting Roundtable, "Failures to Launch Mesenchymal Stromal Cell Therapies: What's the Path Forward?"

Robb, K, Viswanathan, S. Cytotherapy. October 2023. Click here for publication.


Proteomic and genomic profiling of plasma exosomes from patients with ankylosing spondylitis

Tavasolian F, Lively S, Pastrello C, Tang M, Lim M, Pacheco A, Qaiyum Z, Yau E, Baskurt Z, Jurisica I, Kapoor M, Inman RD. Ann Rheum Dis. Click here for publication.


Risankizumab for the treatment of active psoriatic arthritis in adults

Nakamura A, Chandran V. Expert Rev Clin Immunol. December 2023. Click here for publication.


Systemic lupus erythematosus and damage: What has changed over the past 20 years?

Muñoz-Grajales C, Yilmaz EB, Svenungsson E, Touma Z. Best Pract Res Clin Rheumatol. November 2023. Click here for publication.


Time trends and patterns in opioid prescription use following Orthopedic Surgery in Ontario, Canada, from 2004/2005 to 2017/2018: a population-based study.

Canizares M, Power JD, Perruccio AV, Veillette C, Mahomed N, Rampersaud YR. BMJ Open. November 2023. Click here for publication.


The effects of systemic lupus-related cognitive impairments on activities of daily living and life role participation: a qualitative framework study

Barraclough M, Howe A, Soberanis A, Kakvan M, Chattu V, Bani-Fatemi A, Engel L, Vitti M, Nalder E, Goverover Y, Gignac M, Bonilla D, Nielsen W, Anderson N, Tartaglia C, Nowrouzi-Kia B, Touma Z. ACR Open Rheumatol. November 2023. Click here for publication.


Three Decades of Advancements in Osteoarthritis Research: Insights from Transcriptomic, Proteomic, and Metabolomic Studies

Rai MF, Collins K, Lang A, Maerz T, Geurts J, Romero CR, June R, Ramos Y, Rice S, Ali SA, Pastrello C, Jurisica I, Appleton T, Rockel J, Kapoor M. Osteoarthritis and Cartilage. December 2023. Click here for publication.


Tumor Cell-Intrinsic c-Myb Upregulation Stimulates Antitumor Immunity in a Murine Colorectal Cancer Model.

van Gogh M, Glaus Garzon JF, Sahin D, Knopfova L, Benes P, Boyman O, Jurisica I, Borsig L. Cancer Immunol Res. October 2023. Click here for publication.


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