Trial Phases
Treatment Lines
Cancer Stages
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This is a dual arm, single centre, investigator initiated study to investigate the use of FAZA-PET in combination with MRI. FAZA is an investigational radiotracer used in PET scans. FAZA PET/MRI will be used to measure hypoxia in sarcoma t ...

Principal Investigator:

Dr. David Shultz


Disease Site Group:

Sarcoma

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Sarcoma which has spread to the lungs is most often treated with surgery. Even with surgery, most patients will not be cured and will die from their disease, probably because of small cancer cells that are present in the lungs at the time ...

Principal Investigator:

Dr. Marcelo Cypel


Disease Site Group:

Sarcoma

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This study is open to adults with a type of cancer called dedifferentiated liposarcoma (DDLPS). They can join the study if their tumours are positive for MDM2. The purpose of this study is to find out whether a medicine called brigimadlin ...

Principal Investigator:

Dr. Albiruni Razak


Disease Site Group:

Sarcoma

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The purpose of this study is to evaluate the safety, feasibility, and acceptability of a structured, supervised exercise program combined with standard palliative radiotherapy for patients with painful non-spine bone metastases (NSBM).

Principal Investigator:

Dr. Michael Yan


Disease Site Group:

Sarcoma

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This is a Phase 3, open-label, international, multicenter study of CGT9486 in combination with sunitinib. This is a multi-part study that will enroll approximately 442 patients. Part 1 consists of two evaluations: 1) confirming the dos ...

Principal Investigator:

Dr. Albiruni Razak


Disease Site Group:

Sarcoma

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Study CL3-95031-007 (CHONQUER) is a Phase 3, international, multicenter, double-blind, randomized, placebo-controlled study of orally administered ivosidenib. Participants are required to have a histopathological diagnosis consistent with ...

Principal Investigator:

Dr. Abdulazeez Salawu


Disease Site Group:

Sarcoma

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To compare Overall Survival (OS) for INT230-6 vs United States (US) Standard of Care (SOC) in participants with unresectable or metastatic liposarcoma, undifferentiated pleomorphic sarcoma or leiomyosarcoma who have disease progression pri ...

Principal Investigator:

Dr. Albiruni Razak


Disease Site Group:

Sarcoma

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The participants of this study will be children, adolescents, and young adults with residual osteosarcoma, which cannot be removed completely through surgery. Participants will have achieved a partial response or stable disease at the en ...

Principal Investigator:

Dr. Abha Gupta


Disease Site Group:

Sarcoma

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This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differen ...

Principal Investigator:

Dr. Abdulazeez Salawu


Disease Site Group:

Sarcoma

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The hypoxia > metastasis axis suggests that a DWI-based biomarker of hypoxia incorporating IVIM may be able to predict metastasis in STS patients, ultimately enabling stratification for personalized treatments at the time of diagnostic ...

Principal Investigator:

Dr. David Shultz


Disease Site Group:

Sarcoma

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Last modified: 11/25/2024 8:17 AM
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