Better Health Care is in Our Genes

Better Health Care is in Our Genes

The genes in our body give us important health information. This information c​an guide the choices you and your health care team make about health care for you and your family.

This information also helps researchers to:

  • Study a wide range of questions about how genes can affect health
  • Discover new ways to improve health care for everyone

About the OurGenes Study

OurGenes is a health research study being done by the Princess Margaret Cancer Centre at the University Health Network (UHN) in collaboration with US-based Helix Inc. The aim of the study is to learn how genes can affect your health. Every cell in your body contains DNA. Genes are parts of your DNA and are inherited (passed down) from parent to child.

Sometimes, people inherit genes that have changed ("mutations"). These changes may increase the risk of certain diseases or conditions. Genetic screening can help find changes in your genes.

You will get no-cost genetic screening if you wish to take part in this study.​​​​​​​​​​

Why should I take part in this study?​​​

If you choose to take part, you can learn if you have an increased risk for:

human heart illustration
Hereditary (inherited) breast and ovarian cancer (BRCA1 and BRCA2 genes)
human heart illustration
Hereditary (inherited) colon cancer (Lynch syndrome)
human heart illustration
Heart disease related to high cholesterol (familial hypercholesterolemia)

If your results show an increased risk for any of these conditions, you will be offered an appointment with a health care provider or genetic counsellor at UHN. A genetic counsellor is a medical professional trained to help people understand the results of genetic testing. The genetic counsellor or health care provider will discuss your results and advise you on how to reduce your risk.​​

You may also choose to learn about:

  • Your genetic regional ancestry (where your ancestors come from)
  • How your genes may affect certain traits (for example, your sleep patterns or how your body reacts to caffeine)

Why is it important to know your genetic risks?

Family medical history and standard medical screening do not always detect an increased risk for certain diseases or conditions. Knowing if you have these genetic risks may:

  • Improve health care for you and your family
  • Help your health care team tailor your care to manage these risks

For example, if you have an increased risk of colon cancer, your team may suggest more frequent screening for you and your family.

Note: The genetic screening done through the OurGenes Study does not look at all the possible risks linked to your genes. It does not replace any other genetic testing that your health care team suggests for you.

Helping the Community

Researchers are still learning how genetic screening can help improve health care. By taking part in this study, your genetic information will help develop secure genetics research databases external to UHN. These databases will help researchers study:

  • How genes affect health
  • The causes of certain diseases
  • The best treatments to help people live longer and healthier lives

Over time, these databases may help researchers improve health care for everyone.

Partnering with Helix
  • Helix as a Partner: Helix is a partner in the study with the Princess Margaret Cancer Centre at UHN and a population genomics company based in the US. Population genomics is the study of the DNA of many people across various populations. Helix conducts genetic testing and stores the results in the Helix Research Network database located in the US.
  • Helix Research Network (HRN): Your genetic and health data will be securely stored in the United States within the HRN database for future research by Helix, UHN, and other Helix partners, including collaborating health care institutions. The Helix Research Network includes various health systems offering community health research studies. OurGenes is one such study within the HRN.​
  • Data Storage in the US: Data from your UHN health records will be stored indefinitely by Helix in the HRN for future research approved by UHN and Helix. Information that directly identifies you (such as your name, email, etc.) will be removed from your medical record and genetic data and a code will be assigned instead - this is called coded information. Helix will store your personal health information (for example, your medical record number (MRN), name, date of birth, email, and phone number) separately from the coded information. Personal identifiers are collected to facilitate your enrollment in the OurGenes Study. By participating in the OurGenes Study, you would be consenting to the collection and storage of your genetic and medical record data (which will be sent from UHN to Helix for a period of 10 years and stored at Helix indefinitely).
  • Future Research: By participating, you agree to the use of your coded information, which includes your genetic screening results and UHN health record information, in future studies. This coded information will not contain any identifying details, such as your name or email address. Helix partners, other than UHN, and third parties may also use this coded information for research purposes. Please refer to the 'Who else may use my Helix Research Network information?' subsection of the 'Privacy and Data Protection' section of the FAQs for further information on third parties.
  • Traits and Ancestry Information: If you choose to sign up for a Helix Account (optional), in addition to your genetic screening results, you will also get information about your traits and ancestry.

For further information, please review the 'Privacy and Data Protection' section within the FAQs page. ​​​​​​​​​

Follow These Steps to Join the OurGenes Study

1

Confirm Your Identity

If you would like to join the OurGenes Study, click the 'Get Started Today' button at the bottom of this page. This link will take you to your myUHN patient portal to confirm your identity.

Read More

Once your identity is confirmed by UHN, you will automatically be taken to the Helix website. This will result in some information about you (name, MRN, date of birth, email, phone number, and the fact that you’re a UHN patient) being submitted by UHN to Helix for the purpose of validating your identity. If you choose not to complete the enrollment process or are not eligible for the study, Helix will delete your personal information 60 days after receiving it.

Note: You may be able to take part in the study even if you do not have a myUHN account. Please contact the OurGenes study team if this applies to you. The study team will explain your options.

2

Confirm Your Eligibility

Once you log into myUHN, you will need to answer a few questions about your eligibility. Eligibility is the list of criteria or rules that define who can and who cannot join the study.

Read More

You can join the OurGenes Study if you:

  • Are a UHN patient, or have ever been treated at UHN
  • Are 18 years or older
  • Have never had a stem cell or bone marrow transplant with cells from a donor (allogeneic)
  • Do not have an active hematologic (blood) cancer or condition, such as leukemia, lymphoma, myelodysplastic syndrome (MDS), or myeloproliferative neoplasm (MPN) (Note: If you do have a history of one of these conditions, you are still eligible to join the study if you have completed treatment and are in remission.)
3

Review and Sign the Research Consent Form

If you are eligible, you will need to review and sign a research consent form.

Read More

The consent form ensures you understand what the study is about and what is required of you if you choose to participate. If you have any questions about the study or the consent form, contact the OurGenes study team by email at OurGenes@uhn.ca or call 437 676 3576.

The consent form will be hosted on the Helix platform. Helix will store the signed consent forms indefinitely as evidence that an individual has completed the consent process and for inspection purposes during scheduled regulatory monitoring visits. Of note, UHN will also receive a copy of the signed consent form which will be stored in your UHN medical record.​

4

Provide a Blood Sample

Once enrolled (have completed the consent process), you will need to provide a blood sample.

Read More

You can provide your blood sample at any UHN blood lab. If you are having other blood work done at UHN, you can provide your sample for this study at the same time.

Once collected, the UHN study team will send your blood sample to Helix for genetic testing and data retention in the Helix Research Network (HRN) database located in the US. 

Once Helix gets your blood sample, they will sequence your DNA. DNA sequencing looks at the genetic information within your DNA or an entire set of genes to help us learn how our genes work. Helix will retain any left-over samples after genetic testing has been completed for quality control and process improvement purposes.​

5

Get Your Results

You will get your results 8-12 weeks after you provide your blood sample.

Read More​​

Once your results are ready, you will get a message through myUHN. You can then view your results through myUHN. Your results will also be sent to your UHN Electronic Medical Record and the UHN OurGenes study team. These results will also be retained by Helix.

Around 1-2% of people (one to two out of 100) will have an inherited risk for:

  • Hereditary (inherited) breast and ovarian cancer (BRCA1 and BRCA2 genes) 
  • Hereditary (inherited) colon cancer (Lynch syndrome) 
  • Heart disease related to high cholesterol (hypercholesterolemia)

If your results show that you are at an increased risk for any of these conditions, you will be offered an appointment with a health care provider or genetic counsellor at UHN. The genetic counsellor or health care provider will discuss your results with you and advise on how to reduce your risk.​

OurGenes will always take great care to protect your privacy

OurGenes will always take great​​ care to protect your privacy​

You can find more information on how your privacy will be protect​ed in the FAQs page and in the research consent form.

Get Started Now

Confirm your identity and Get Started today

The following will take you to your myUHN account to confirm your identity. Once your identity is confirmed by UHN, you will automatically be taken to the Helix website. This will result in some information about you (your name, MRN, date of birth, email, phone number, and the fact that you’re a UHN patient) being submitted by UHN to Helix for the purpose of validating your identity.

Get Started with OurGenes

​​








Contact

Contact

For questions about the study, you can contact the OurGenes study team at OurGenes@uhn.ca or 437 676 3576.

For questions related creating or accessing an optional Helix Account, please contact Helix customer support by phone, email or by filling out an online request.



​​


https://www.uhn.ca/PrincessMargaret/Education/Continuing_Education_Programs/Pages/continuing_education_programs.aspx
Last reviewed:
Last modified: 9/4/2025 11:14 AM
Back to Top