Psilocybin-Assisted Existential, Attachment and RelationaL (PEARL) Therapy for End-of-Life Distress in Patients with Advanced Cancer

We have developed a new method of psychedelic-assisted psychotherapy for end-of-life distress in patients with advanced cancer called PEARL Therapy. A series of studies to be conducted at the Princess Margaret Cancer Centre will examine the feasibility, safety and efficacy of PEARL Therapy.

Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Caregivers

Caregivers of advanced cancer patients often report higher levels of distress than the patients themselves. We are planning pilot studies of PEARL therapy for caregivers of advanced cancer patients and for bereaved caregivers.

Psilocybin-assisted Psychotherapy for Body Dysmorphic Disorder

Body Dysmorphic Disorder (BDD) is a severe psychiatric condition characterized by a belief in imagined ugliness. It impacts 2% of the population and is often resistant to treatment and associated with high rates of depression and suicidality. In collaboration with the Centre for Addiction and Mental Health, we will investigate psilocybin-assisted psychotherapy for treatment-resistant BDD.

Experiential Training in Therapists Learning Psychedelic-assisted Psychotherapy

This mixed-methods pilot study will investigate the role of experiential training for therapists in our certificate program by providing trainees with the option to receive a course of psilocybin-assisted psychotherapy.

Integration Project

The Centre will examine how people integrate their psychedelic experiences in the community via surveys, semi-structured interviews and focus groups. This work will lead to the development of best practice guidelines and psychotherapeutic approaches to support integration.

To make a donation to support the Nikean Psychedelic Psychotherapy Research Centre, please visit the UHN Foundation.