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About the Multi-Organ Transplant Program

​​​​The Multi-Organ Transplant Program (MOT) at the University Health Network (UHN) is the largest and most comprehensive transplant program in Canada.

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All MOT patient and staff stories, press releases, press conferences, interviews, and coverage are managed through
UHN's Public Affairs team​ at Toronto General Hospital.​​​​​​​​​​​​

As one of the top five programs in North America, we are known around the world as experts in kidney, liver, lung, heart and pancreas and intestinal transplant procedures.

The MOT program uses a coordinated team approach to care for all transplant patients. This focus helps the program develop unparalleled advances in transplantation and it provides the best medical and surgical care for our patients from all over the world. MOT also attracts and develops some of the world’s best leaders in surgical innovation, transplant medicine, nursing, and related areas of study. 


The MOT program is a national and global referring centre for patients who need some of the most complex transplants.

Patients come to UHN’s Multi-Organ Transplant Program because:

  • They are offered exceptional care from our dedicated multidisciplinary team.
  • We achieve remarkable results because we know how to effectively turn new research from the laboratory to the clinic.
  • We have better 1 year, 5 year and 10 year survival rates and surgical results compared to international standards.
  • We have the best patient outcomes among transplant centres anywhere in the world.

A dedicated team of MOT surgeons, doctors, nurses and other health care professionals make sure that all our patients receive the best possible individualized care. This begins before transplant, continues during surgery, and extends beyond recovery.

Our unique approach leads excellent short and long-term outcomes when compared to the U.S.

MOT Team 

Research conducted by the MOT program focuses on improving health outcomes for people with organ transplants. Our ultimate goal is to be able to transplant organs that a person's body will never reject. The MOT program continues to research new strategies to prevent acute and chronic organ rejection, and reduce the need for lifelong immunosuppressant medications.

The MOT program is pioneering many research projects that are changing the way in which transplant patients are treated and cared for. Some of these include:

  • Transplant Organ Repair Centre
    UHN's MOT program has developed the world's first centre which expands the ability to repair donor organs such as the lungs, liver, kidney, and heart.  This increases the number of organs available for transplant.
  • Understanding and Overcoming Donor Organ Rejection
    The MOT program is exploring a comprehensive "bench to bedside"  research program to help us understand:
    • Why the body rejects donated organs
    • What will help reduce or eliminate the need for long-term therapy which suppresses the immune system of recipients (tolerance)
  • Transplant Biobank
    A state-of-the-art bank of thousands of tissue samples. The MOT program is currently finding ways to improve the health and quality of life for transplant patients.
  • Artificial Lungs
    The MOT program is the only hospital in Ontario with a "bridge to transplant" program - an artificial lung technology. UHN's MOT program is the leading referral centre in Canada for patients with acute lung failure.
  • Stem Cell Therapy
    In partnership with the UHN McEwen Centre for Regenerative Medicine, the MOT program  is working to develop clinical research using stem cell products for the treatment of diabetes and advanced liver disease, as well as to repair organs before transplantation.
  • Whole Organ Bioengineering
    MOT experts are researching techniques to bioengineer whole organs using a transplant recipient's own stem cells.
  • Transplant Infectious Diseases
    The MOT program is assessing factors that lead to infections in transplant patients and how best to prevent and treat them.​

UHN's MOT program offers a wide range of educational opportunities for medical professionals and attracts interest from the brightest doctors and surgeons around the world. Our program has strong ties to the University of Toronto and offers:

  • A number of fellowships for physicians interested in surgical or medical clinic training and research in the fields of transplantation and immunology.
  • Medical rounds for organ-specific transplant groups and a general session of interest to transplant professionals from all disciplines are held each week.
  • Journal clubs and medical orientation also contribute to the educational development of staff and students.
  •  Nursing placements including:
    • Nurse Practitioner placements in lung, heart and liver transplant.
    • Nursing undergraduate placements for students consolidating in their final year.
    • A comprehensive 5-day inter-professional transplant orientation for all nursing students and new hires.
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