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Krembil Neuroscience Centre (KNC)
Neuro-Ophthalmology - Research
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In addition to caring for patients in clinics, we are engaged in research to better understand the anatomy and physiology of ocular motor (eye movement) and vestibular (equilibrium) control.
Research
Through the Krembil Neuroscience Centre and Toronto Western Research Institute, this research program has sustained continuous support from the Medical Research Council of Canada for 28 years (from 1974 through 2002) at Toronto Western Hospital.
The physiology of disordered gaze and vestibulo-ocular reflex functions are being investigated in normal humans and patients with lesions of the cerebral hemispheres, brainstem and cerebellum and in patients with acquired and developmental strabismus. Parallel studies in animals are performed in our vestibular-ocular motor neurophysiology laboratory. Correlation of disorders of saccadic eye movement, head movement, smooth pursuit, and vestibulo-ocular reflex disorders with the site, nature and evolution of brain lesions:
- Clarifies the anatomical and physiological bases of ocular motor and vestibular control in normal humans and animals,
- Provides sensitive quantitative parameters of abnormal brain function,
- Establishes bases for understanding and managing disabilities suffered by patients with disorders of vision, gaze, and equilibrium caused by diseases of the nervous system.
Useful Links
For more information on neuro-otology and neuro-ophthalmology research at the Krembil Neuroscience Centre, visit the Toronto Western Research Institute.
